Notes
If mixing LAs, we recommend that the safest practice is not to exceed 100% of the combined maximum dose.14, 15
Lidocaine 2% with adrenaline: A maximum dose of 7 mg/kg; not to exceed 500 mg per dose.5
Levobupivacaine/Bupivacaine with adrenaline: A maximum dose of 3 mg/kg; not to exceed 225 mg per dose.5
Adrenaline: There were no differences in blood flow reduction between epinephrine concentrations of 1:100,000, 1:200,000, and 1:400,000.16 Based on a review of the literature, concentrations between 1:50,000 and 1:400,000 are equally effective and provide superior vasoconstriction compared with more dilute solutions.17
IBW: ideal body weight; LBW: lean body weight; BNF: British National Formulary; SOBA: The Society for Obesity and Bariatric Anaesthesia;
AoA: Association of Anaesthetists (UK)
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